THE USE OF BAYPAMUN-N IN CROWDING-ASSOCIATED INFECTIOUS RESPIRATORY-DISEASE - EFFICACY OF BAYPAMUN-N (FREEZE-DRIED PRODUCT) IN 2-WEEK-OLD VEAL CALVES

The efficacy of an immunomodulator, Baypamun N, was tested in 10-20-da y-old veal calves from different farms, which were exposed to stress b y transport and commingling (crowding). Verum and placebo animals (n = 50, each group) received three intramuscular injections of the invest igational products (days 0, 2, 4) starting the day of arrival on the f arm. Data from 49 calves in each group could be used for statistical e valuation. The incidence of acute bovine respiratory disease was antic ipated to be high during the first 2 weeks after arrival on farm based on experience from other years. The clinical scores in the Baypamun N group were significantly reduced by 52.7% (P < 0.001) compared to the placebo group. The number of antibiotic treatments was significantly reduced by 53.8% (P < 0.001) in the Baypamun N group. Of the calves tr eated with Baypamun N, 51.02% remained untreated with antibiotics duri ng the first 2 weeks after arrival on the farm compared with only 16.3 % of the placebo treated control calves (P < 0.001).