CONSERVATIVE MANAGEMENT OF PATIENTS WITH HISTOLOGICAL INCOMPLETE EXCISION OF CERVICAL INTRAEPITHELIAL NEOPLASIA AFTER LARGE LOOP EXCISION OF TRANSFORMATION ZONE
Ks. Chan et al., CONSERVATIVE MANAGEMENT OF PATIENTS WITH HISTOLOGICAL INCOMPLETE EXCISION OF CERVICAL INTRAEPITHELIAL NEOPLASIA AFTER LARGE LOOP EXCISION OF TRANSFORMATION ZONE, Chinese medical journal, 110(8), 1997, pp. 617-619
Objective To evaluate conservative management of patients with histolo
gical incomplete excision of CIN after large loop excision of transfor
mation zone (LLETZ). Methods Two hundred and seventeen patients with h
igh grade CIN were treated with LLETZ from October it 1992 to December
31, 1994. Fifty-three patients (24. 4%) had incomplete excision on hi
stology. All patients were followed up cytologically every 3 to 6 mont
hs during the first 18 months and then yearly till December 1996. Thos
e patients with positive endocervical margins were followed up with bo
th cervical smear and endocervical smear. Results The mean follow-up d
uration was 30. 4 months. Ten patients were found to have persistent o
r recurrent disease. Five patients had second LLETZ and complete excis
ion was achieved in 4 of them, one patient had cone biopsy and two had
hysterectomy. One patient was found to have stage I a cervical cancer
. Conclusion A report of incomplete excision of CIN after LLETZ calls
for follow-up with cytology and colposcopy and not aggressive retreatm
ent.