Mh. Chin et al., DIFFERENCES IN GENERALIST AND SPECIALIST PHYSICIANS KNOWLEDGE AND USEOF ANGIOTENSIN-CONVERTING ENZYME-INHIBITORS FOR CONGESTIVE-HEART-FAILURE, Journal of general internal medicine, 12(9), 1997, pp. 523-530
OBJECTIVE: To quantify the extent and determinants of underutilization
of angiotensin-converting enzyme (ACE) inhibitors for patients with c
ongestive heart failure, especially with respect to physician specialt
y and clinical indication. DESIGN: Survey of a national systematic sam
ple of physicians, PARTICIPANTS: Five hundred family practitioners, 50
0 general internists, and 500 cardiologists. MEASUREMENTS AND MAIN RES
ULTS: Physicians' choice of medications were determined for four hypot
hetical patients with left ventricular systolic dysfunction: (1) new-o
nset, symptomatic; (2) asymptomatic; (3) chronic heart failure, on dig
italis and diuretic; and (4) asymptomatic, post-myocardial infarction.
For each patient, randomized controlled trials have demonstrated that
ACE inhibitors decrease mortality or the progression of symptoms, Amo
ng the 727 eligible physicians returning surveys (adjusted response ra
te 58%), approximately 90% used ACE inhibitors for patients with chron
ic heart failure who were already taking digitalis and a diuretic. How
ever, family practitioners and general internists chose ACE inhibitors
less frequently (p less than or equal to .01) than cardiologists for
the other indications. Respective rates of ACE inhibitor use for each
simulated patient were new-onset, symptomatic (family practitioners 72
%, general internists 76%, cardiologists 86%); asymptomatic (family pr
actitioners 68%, general internists 78%, cardiologists 93%): and asymp
tomatic, postmyocardial infarction (family practitioners 58%, general
internists 70%, cardiologists 94%). Compared with generalists, cardiol
ogists were more likely (p less than or equal to .05) to increase ACE
inhibitors to a target dosage (45% vs 26%) and to tolerate systolic bl
ood pressures of 90 mm Hg or less (43% vs 15%). CONCLUSIONS: Compared
with cardiologists, family practitioners and general internists probab
ly underutilize ACE inhibitors, particularly among patients with decre
ased ejection fraction who are either asymptomatic or post-myocardial
infarction, Educational efforts should focus on these indications and
emphasize the dosages demonstrated to lower mortality and morbidity in
the trials.