10-YEAR FOLLOW-UP-STUDY OF NEONATAL HEPATITIS-B IMMUNIZATION - ARE BOOSTER INJECTIONS INDICATED

Authors
RESTI M AZZARI C MANNELLI F ROSSI ME LIONETTI P VIERUCCI A
Citation
M. Resti et al., 10-YEAR FOLLOW-UP-STUDY OF NEONATAL HEPATITIS-B IMMUNIZATION - ARE BOOSTER INJECTIONS INDICATED, Vaccine, 15(12-13), 1997, pp. 1338-1340
Citations number
13
Categorie Soggetti
Immunology
Journal title
Vaccine → ACNP
ISSN journal
0264410X
Volume
15
Issue
12-13
Year of publication
1997
Pages
1338 - 1340
Database
ISI
SICI code
0264-410X(1997)15:12-13<1338:1FONHI>2.0.ZU;2-X
Abstract
One hundred and fourteen children, born to HBsAg-positive mothers rece ived in the first year of life passive active prophylaxis for hepatiti s B virus (HBV). They have been followed up to 10 years. A booster dos e given in a cohort at the 5th year does not seem to increase protecti on against HBV. No difference in immunological memory was present at t he 10th year between the group of children who had received the booste r dose at 5 years of age and the group who did not. (C) 1997 Elsevier Science Ltd.