A sizeable, feedforward, GABAergic projection exists from the inferior
colliculus to the medial geniculate body in cats. We compared the dim
ensions of GABA-immunoreactive and non-immunoreactive axons in the bra
chium of the cat inferior colliculus, and demonstrate that GABA-immuno
reactive axons are among the largest of brachial axons. We propose tha
t, based on their large size, GABAegic tectothalamic axons provide a s
ubstrate for rapid feedforward inhibition of geniculate neurons. (C) 1
997 Elsevier Science B.V.