R. Sas et C. Dawes, THE INTRAORAL DISTRIBUTION OF UNSTIMULATED AND CHEWING-GUM-STIMULATEDPAROTID-SALIVA, Archives of oral biology, 42(7), 1997, pp. 469-474
The objective was to determine the percentage contribution of parotid
saliva to whole saliva and to the saliva at 11 sites in the mouth, whe
n flow rate was unstimulated or stimulated with chewing-gum. The marke
r substance used was alpha-amylase, as this is in much higher concentr
ation in parotid saliva than in secretions from other salivary glands.
Formulae were derived for calculation of the minimum, maximum, and me
an percentage contributions of parotid saliva to saliva in different a
reas of the mouth. The results, from 10 individuals, showed that the c
ontributions of parotid to unstimulated and stimulated whole saliva av
eraged 30.1% and 35.6%, respectively, whereas the corresponding values
for samples from the region vestibular to the upper molars were 56.1%
and 61.4%, but only 2.8% and 6.8% for samples from an area vestibular
to the upper incisors. Thus parotid saliva was not evenly distributed
throughout the mouth. Stimulated samples mostly contained significant
ly higher proportions of parotid saliva, but the distribution of the p
arotid saliva was still extremely variable. Because the different regi
ons of the mouth are not exposed to the same fluid environment, this m
ay influence the site-specificity of supragingival calculus deposition
and of various diseases such as dental caries. (C) 1997 Elsevier Scie
nce Ltd.