ACTIVATION AND INACTIVATION STEPS IN THE VISUAL TRANSDUCTION PATHWAY

Authors
PALCZEWSKI K SAARI JC
Citation
K. Palczewski et Jc. Saari, ACTIVATION AND INACTIVATION STEPS IN THE VISUAL TRANSDUCTION PATHWAY, Current opinion in neurobiology, 7(4), 1997, pp. 500-504
Citations number
40
Categorie Soggetti
Neurosciences
Journal title
Current opinion in neurobiology → ACNP
ISSN journal
09594388
Volume
7
Issue
4
Year of publication
1997
Pages
500 - 504
Database
ISI
SICI code
0959-4388(1997)7:4<500:AAISIT>2.0.ZU;2-D
Abstract
Recent genetic, biochemical and electrophysiological evidence has prov ided insights into the molecular identity of the substance responsible for bleaching desensitization in vision, Studies examining the molecu lar defects that cause delayed dark adaptation suggest that the desens itizing substance is recognized by rhodopsin kinase and/or arrestin an d, therefore, is probably a complex comprising all-trans-retinal and o psin.