IN-VITRO SUSCEPTIBILITIES TO AMPHOTERICIN-B, ITRACONAZOLE, AND MICONAZOLE OF FILAMENTOUS FUNGI ISOLATED FROM PATIENTS WITH CYSTIC-FIBROSIS

Authors
HENNEQUIN C BENAILLY N SILLY C SORIN M SCHEINMANN P LENOIR G GAILLARD JL BERCHE P
Citation
C. Hennequin et al., IN-VITRO SUSCEPTIBILITIES TO AMPHOTERICIN-B, ITRACONAZOLE, AND MICONAZOLE OF FILAMENTOUS FUNGI ISOLATED FROM PATIENTS WITH CYSTIC-FIBROSIS, Antimicrobial agents and chemotherapy, 41(9), 1997, pp. 2064-2066
Citations number
19
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
41
Issue
9
Year of publication
1997
Pages
2064 - 2066
Database
ISI
SICI code
0066-4804(1997)41:9<2064:ISTAIA>2.0.ZU;2-F
Abstract
The antimicrobial activities of amphotericin B, itraconazole, and mico nazole against 101 filamentous fungi from patients with cystic fibrosi s were tested by a reproducible microdilution method. Itraconazole was very active against Aspergillus species and Scedosporium species (MIC at which 90% of the isolates were inhibited [MIC90], 0.06 to 0.5 mg/l iter), whereas amphotericin B was Less effective (MIC90, 0.5 to 8 mg/l iter).