A. Meyerlindenberg et al., MEGADOLICHO BASILAR ARTERY - RELEVANCE FOR NEUROLOGICAL INTENSIVE-CARE AS AN INDICATOR OF BRAIN-STEM ISCHEMIA, Nervenarzt, 68(8), 1997, pp. 674-677
An ectasia and enlargement of the basilar artery by a fusiform aneurys
m is called megadolicho basilaris. We report five cases with this cond
ition identified at our clinic since 1989, reflecting an incidence of
0,05 percent (5/9300 scans). All patients presented with an acute brai
nstem syndrome (medullary in 2, pontine in 1 and pontomedullary in 2 p
atient). With one exception, all cases required intensive care due to
respiratory insufficiency. Two patients died, one required total care,
and two patients made a good recovery, one of these under therapeutic
anticoagulation. All but one patient experienced additional episodes
of cerebrovascular ischemia before or after presentation. Vascular ris
k factors were found in four patients. The detection of a megadolicho
basilaris identifies a patient subgroup that is highly prone to verteb
robasilar ischemia and therefore of high significance for neurological
intensive care medicine. Recurrence rate for ischemia is high. While
even a severe brainstem syndrome may be reversed under anticoagulation
in the individual case, presence of multiple vascular risk factors of
ten prevents the employment of this treatment modality.