Objective. We report the off-line calculation of the vascular complian
ce of the finger and suggest the continuous on-line use of this method
ology as an aid to monitoring the peripheral vascular resistance. This
method consists of the simultaneous analysis of the waveform signals
from the pulse oximeter monitors and the arterial pressure as indicato
rs of ''volume'' and pressure respectively to continuously calculate t
he vascular ''compliance'' (volume change per unit pressure change). T
his should be seen as a ''relative compliance'' as the pulse plethysmo
graph signal is not calibrated. This new methodology allows for contin
uous monitoring of peripheral vascular compliance as a beat-to-beat in
dicator of peripheral vascular resistance. The vaso-constrictors, phen
ylephrine and ephedrine, were shown to decrease the compliance as pred
icted. Methods. The arterial pressure and pulse oximeter waveforms wer
e obtained during routine anesthetic care. The waveforms were collecte
d with a computer data-acquisition system and then analyzed ''off-line
'' as an indirect indicator of total vascular tone. Demographic and cl
inical information including drug administration were recorded. Result
s. A case report is presented using this new: form oi analysis. Vascul
ar compliance changes induced by phenylephrine and ephedrine were stud
ied. A dose response curve of peripheral vascular compliance to phenyl
ephrine was generated from these dat;. Conclusions. By plotting the pu
lse oximeter waveforms versus the arterial waveforms, multiple volume
versus pressure (relative compliance) loops were obtained. Analysis of
these loops may assist in the monitoring oi vascular compliance.