Both on a global and a regional basis, the World Health Organization (
WHO) has set prominent goals for the nun of the millennium on the redu
ction of harms associated with licit and illicit drugs. Gauging what t
he world and its different regions are doing with respect to these spe
cific public health goals is hindered by a conceptual problem: there i
s no clear concept and consistent way of defining or measuring 'harm'
related to drugs, licit or illicit. In many instances, 'harm' is equat
ed with substance use prevalence. Often, especially outside the develo
ped world, basic harm data is not even available. Globally, a conceptu
ally clear and consistently applied scheme of harm measurement related
to licit and illicit drugs is needed, acknowledging the fact that dru
g-related harms occur at different individual and social levels as wel
l as over different periods of time. Harms must also be recognized as
an outcome of interactions between the substance user, the drug itself
, and the physical and social environment. Looking at available macro-
indicators of harm, it must be concluded with, we do not seem to be 'o
n track' globally in reducing harms related to drugs in accordance wit
h the WHO goals. For alcohol and tobacco, trends for increased harm ar
e just starting to show in the developing world, and will worsen over
the next couple of decades. For illicit drugs, failing drug control po
licies have result in dramatically negative developments for public he
alth, especially with respect to HIV infections and drug-related death
s, in the developed as well as developing world.