There is a clear association between the dorsal lithotomy position and
the development of a postoperative compartment syndrome. Compartment
syndrome occurs when elevated pressure in an osteofascial compartment
compromises local perfusion and often results in neurovascular damage
and permanent disability. Surgeons must recognize this association and
provide appropriate preventative measures, have a high index of suspi
cion in all patients, and be prepared to make an early diagnosis when
it is encountered. We will report four cases we encountered, discuss t
he etiology, analyze the literature, and propose a modification on pat
ient positioning that has minimized the incidence of compartment syndr
ome at our institution. A variety of intraoperative events, including
hypotension, hypoxemia, leg elevation, hip and knee flexion, direct pr
essure, and compressive bandages may all contribute to compartmental i
schemia. Ischemia is followed by reperfusion, capillary leakage from t
he ischemic tissue, and a further increase in tissue edema. Increased
edema causes further embarrassment of perfusion and perpetuation of th
e cycle, ultimately resulting in neuromuscular compromise secondary to
ischemia. To prevent this destructive cycle, emphasis must be placed
on maintaining a high index of suspicion in all patients, minimizing l
eg elevation, and on the importance of early diagnosis and interventio
n.