Background: Genitourinary tuberculosis (GUTB) has been reported to acc
ount for 20% to 73% of all cases of extrapulmonary tuberculosis in the
general population but is much rarer in children, GUTS is a form of s
econdary tuberculosis with vague symptoms. Surgical intervention is re
quired in a minority of cases. Methods: Nine cases of genitourinary tu
berculosis (GUTB) were diagnosed and treated from 1988 to 1995. The ag
e of the patients ranged from 5 to 12 years. There were five boys and
four girls. Presenting features were diverse and included gross hematu
ria in 44% of cases and epididymoorchitis in 22% of cases. Rarer prese
nting features included acute renal failure, staghorn calculus, and py
onephrosis. Associated or past history of tuberculosis was present in
three patients. Conclusive diagnosis was made on the basis of isolatio
n of mycobacterium tuberculosis, histopathology, or cystoscopy in eigh
t patients, whereas one patient was given a therapeutic trial based on
clinical manifestations. Results: Response to antitubercular drug the
rapy was gratifying. Excisional surgery in the form of nephrectomy was
needed in one patient, whereas another underwent bilateral ureteric r
eplacement with ileal loops for multiple ureteric strictures. Conclusi
ons: The wide variety of presenting features and pathological lesions
that result from GUTB are emphasized. The diagnosis of GUTS must be su
spected in patients who present with hematuria (gross or otherwise), e
pididymoorchitis, and patients with long segment or multiple ureteric
strictures. in view of the anticipated resurgence in tuberculosis caus
ed by the prevalence of aquired immunodeficiency syndrome the pediatri
c urologist must be aware of the pathophysiology and clinical spectrum
of this disease. Copyright (C) 1997 by W.B. Saunders Company.