EMBRYONAL RHABDOMYOSARCOMA OF THE LUNG ARISING IN CYSTIC ADENOMATOID MALFORMATION - CASE-REPORT AND REVIEW OF THE LITERATURE

Rhabdomyosarcoma (RMS) of the lung is a very rare lesion, but the asso ciation with cystic adenomatoid malformation (CCAM) is unlikely to be a coincidence. Although the etiologic factors predisposing infants and children to pulmonary neoplasms are unknown, pulmonary developmental abnormalities may play a pathogenetic role. A case of embryonal pulmon ary RMS is described, which was discovered within a congenital CCAM in a 22-month-old child. The hypothesis regarding histogenesis of this n eoplasm are also briefly discussed. Because of the risk of malignant c hange, early removal of the congenital cystic lesions of the lung is a dvisable. Copyright (C) 1997 by W.B. Saunders Company.