Background. Patients who present with chest pain but have normal coron
ary angiography and who are told by their cardiologist that they do no
t have heart disease, have a poor symptomatic, psychological and quali
ty of life outcome and remain concerned about a serious cause of their
symptoms. They frequently complain they have not had enough informati
on. The study aimed to test the effectiveness and acceptability of a b
rief psychological intervention based on cognitive behavioural princip
les. Methods. Consecutive patients with chest pain and normal angiogra
ms were assessed and invited to take part in a randomized controlled e
valuation. The intervention consisted of an individualized information
and discussion session by a specially trained cardiac nurse, together
with a handout and cassette providing information and advice and tele
phone follow-up to discuss progress, answer questions and reiterate ad
vice. Results. The treatment proved to be unacceptable to some patient
s and there was no evidence of efficacy. Conclusions. Implications for
the preparation of patients undergoing angiography and for the timing
and delivery of information and advice following a negative result ar
e discussed.