Mood disorders are common in women. A prepregnancy personal history of
mood disorder (bipolar or major depression), premenstrual syndrome, o
r (possibly) postpartum blues places a woman at high risk for a postpa
rtum exacerbation of symptoms. Untreated or unrecognized postpartum mo
od disorders can lead to serious psychologic and social consequences,
in some cases even leading to suicide or infanticide. Women at risk fo
r postpartum mood disorders need to be referred for psychiatric consul
tation before pregnancy and parturition. Informed, professional collab
oration offers the best opportunities for prevention, as well as the e
arliest recognition and treatment of emergent symptoms.