SELF-SORTING OF WHITE BLOOD-CELLS IN A LATTICE

When a drop of human blood containing red and white blood cells is for ced to move via hydrodynamic forces in a lattice of channels designed to mimic the capillary channels, the white cells self-fractionate into the different types of white cells. The pattern of white cells that f orms is due to a combination of stretch-activated adhesion of cells wi th the walls, stochastic sticking probabilities, and heteroavoidance b etween granulocytes and lymphocytes.