Anhedonia has been proposed as a psychological marker for biological d
epression. In this study, anhedonia was measured in a cohort of chroni
cally depressed outpatients. Levels of anhedonia were similar to those
reported in acutely depressed patients. Anhedonia was significantly c
orrelated with morbid risk of depression in first-degree family member
s, neuroticism, introversion, and dysfunctional attitudes, but not wit
h depression severity or hopelessness scores. In a naturalistic follow
-up study over a 1-year period, while depression severity was signific
antly reduced, anhedonia scores remained constant. The study provides
support for the view that in chronic depression anhedonia may have tra
it-like properties, and that the propensity toward anhedonic responses
may occur irrespective of depressive severity. Copyright (C) 1997 by
W.B. Saunders Company.