Apw. Yuen et al., RESULTS OF SURGICAL SALVAGE OF LOCOREGIONAL RECURRENCE OF CARCINOMA OF THE TONGUE AFTER RADIOTHERAPY FAILURE, The Annals of otology, rhinology & laryngology, 106(9), 1997, pp. 779-782
The aim of this study was to evaluate the efficacy of surgical salvage
of local and nodal recurrence of carcinoma of the oral tongue after r
adiotherapy failure. Of the 47 patients in this retrospective review (
between 1980 and 1992), there were 25 with local recurrence alone, 11
with locoregional recurrence, and 11 with nodal recurrence alone. Ther
e was no operative mortality, and 17% of patients had one or more surg
ical complications, including wound infection, flap necrosis, anastomo
tic leakage, and chest infection. Twenty-nine (62%) patients developed
recurrences in the head and neck region after the salvage operation,
and 9 of them had second surgical salvage operations. At the last foll
ow-up, 53% of patients had died of carcinoma of the tongue and the ove
rall 5-year actuarial survival rate was 43%. The 5-year actuarial surv
ival rates were 39% for local recurrence alone, 27% for locoregional r
ecurrence, and 68% for nodal recurrence alone. Surgical salvage had sa
tisfactory results for patients with oral tongue carcinoma after radio
therapy failure. Close follow-up and early surgical intervention are e
ssential for patients primarily treated with radiotherapy.