ROLE OF DNA MEASUREMENTS OF HEAD AND NECK TUMORS

Authors
MILROY CM FERLITO A DEVANEY KO RINALDO A
Citation
Cm. Milroy et al., ROLE OF DNA MEASUREMENTS OF HEAD AND NECK TUMORS, The Annals of otology, rhinology & laryngology, 106(9), 1997, pp. 801-804
Citations number
30
Categorie Soggetti
Otorhinolaryngology
Journal title
The Annals of otology, rhinology & laryngology → ACNP
ISSN journal
00034894
Volume
106
Issue
9
Year of publication
1997
Pages
801 - 804
Database
ISI
SICI code
0003-4894(1997)106:9<801:RODMOH>2.0.ZU;2-O
Abstract
The measurement of DNA ploidy has been used as a tool to try to determ ine the prognosis of many neoplasms. DNA ploidy can be determined by f low cytometry or image analysis of a tumor. In squamous carcinomas of the head and neck, a poorer prognosis has been associated with nondipl oid tumors. Similar results have been obtained from studies of salivar y gland neoplasms. The role of DNA ploidy as a provider of independent information has yet to be determined. With rarer head and neck tumors , measurement of tumor ploidy has yet to be established as a valuable adjunct to routine light microscopic study.