DANAPAROID FOR CARDIOPULMONARY BYPASS IN PATIENTS WITH PREVIOUS HEPARIN-INDUCED THROMBOCYTOPENIA

Anticoagulation for cardiopulmonary bypass in patients with heparin-in duced thrombocytopenia requires the use of other anticoagulants, We re port a case in whom this was achieved using the heparinoid danaparoid (Orgaran). Based on our experience and a review of the literature, we provide guidelines for managing these rare patients. A danaparoid dose substantially lower than that recommended by the manufacturer may min imize bleeding complications.