2 SUCCESSFUL PREGNANCIES IN A 46,XY PATIENT

Two successful pregnancies (singleton followed by twins) following ovu m donation/in-vitro fertilization in a 46,XY woman have been studied. Although similar cases hav previously been presented: in a pure XY pat ient and in a 45,X/46,XY patient, this case is one in which a subseque nt successful pregnancy has resulted. In such patients, the rate of Ca esarean section appears to be increased, and we postulate that the hyp oplastic nature of the uterus, although able to respond quite well to both exogenous and endogenous hormones to accept and maintain a pregna ncy, may lack the capability to respond fully in labour by dilating ap propriately.