S. Bhattacharya et al., HOW EFFECTIVE IS PATIENT-CONTROLLED ANALGESIA - A RANDOMIZED COMPARISON OF 2 PROTOCOLS FOR PAIN RELIEF DURING OOCYTE RECOVERY, Human reproduction, 12(7), 1997, pp. 1440-1442
Although the conventional method of pain relief during outpatient oocy
te recovery involves physician-administered drugs, patient-controlled
analgesia (PCA) offers an alternative technique with the potential to
give women more control over peroperative analgesia. We conducted a pr
ospective randomized study to compare the effect of fentanyl administe
red either through a PCA delivery system or by a physician. Thirty-nin
e women were randomized to PCA during egg collection while 42 were all
ocated to receive intermittent doses administered by a physician. Pain
was evaluated by means of a 100 mm linear analogue scale. The mean (S
D) pain score in the PCA group was 38.5 (19.8) while in the other grou
p it was 46.1 (21.3) (p =0.1). In the PCA group, 64% of women felt ver
y satisfied with their analgesia as compared with 57% in the non-PCA g
roup (P=0.6). Among the PCA users, 39% of demands were successful. Sig
nificantly more fentanyl (97.5 mu g) was used in the PCA group than in
the other group (84.6 mu g) (P = 0.03). Though intraoperative PCA wit
h fentanyl is an effective alternative to physician-administered techn
iques, many women still fell the need for more analgesia during the pr
ocedure.