OPTIMIZATION WITH EXPERIMENTAL-DESIGN OF NONIONIC, ANIONIC, AND AMPHOTERIC SURFACTANTS IN A MIXED SYSTEM

In a mixture experiment the response depends only on the relative prop ortions of material present in the mixture. In this study, we consider shampoo formulations with three different classes of surface-active a gents: amphoteric, nonionic, and anionic mild surfactants. A major pur pose of this study is to help the formulator with a strategy using a t hree-component simplex-centroid design. This methodology offers the ma ximum return in terms of information about the interplay of multiple f actors while requiring the minimum investment.