Citation
L. Garrido et al., NEW FURANOTERPENOIDS FROM THE SPONGE SPONGIA-OFFICINALIS, Journal of natural products, 60(8), 1997, pp. 794-797
Citations number
21
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy","Chemistry Medicinal
Journal title
ISSN journal
01633864
Volume
60
Issue
8
Year of publication
1997
Pages
794 - 797
Database
ISI
SICI code
0163-3864(1997)60:8<794:NFFTSS>2.0.ZU;2-B
Abstract
The sponge Spongia officinalis from La Caleta, Cadiz, Spain, contains
the new C-21 furanoterpenes furospongin-5 (1) and cyclofurospongin-2 (
2) and the new furanosesterterpene demethylfurospongin-4 (3), in addit
ion to the known terpenoids 4-11. The structures of compounds 1-3 were
elucidated by interpretation of spectral data and chemical interconve
rsions. Furospongin-5 (1) was weakly cytotoxic against the P-388 cell
line (ED50 = 5 mu g/mL).