Ps. Parameswaran et al., SECONDARY METABOLITES FROM THE SPONGE TEDANIA ANHELANS - ISOLATION AND CHARACTERIZATION OF 2 NOVEL PYRAZOLE ACIDS AND OTHER METABOLITES, Journal of natural products, 60(8), 1997, pp. 802-803
Chemical investigation of the methanol extract of the sponge Tedania a
nhelans yielded the two unusual heteroaromatic acids, pyrazole-3(5)-ca
rboxylic acid (2) and 4-methylpyrazole-3(5)carboxylic acid (3), which
are reported for the first time as natural products. The other compoun
ds isolated were p-hydroxybenzaldehyde, phenylacetamide, 3-phenylpropi
onic acid 3-(p-hydroxyphenyl)propionic acid, 3-(p-methoxyphenyl)propio
nic acid, beta-carboline (norharman) (1), and the four diketopiperazin
es pro-val, pro-leu, pro-phe, and pro-tyr.