A. Figueras et al., IN-VITRO IMMUNOSTIMULATION OF TURBOT (SCOPHTHALMUS-MAXIMUS) LEUKOCYTES WITH BETA-GLUCAN AND OR PHOTOBACTERIUM-DAMSELA BACTERIN/, Gyobyo kenkyu, 32(3), 1997, pp. 153-157
Respiratory burst and phagocytic activities of turbot (Scophthalmus ma
ximus) leucocytes were determined after an in vitro incubation of head
kidneys with different doses of yeast glucan and Photobacterium damse
la (formerly Vibrio damsela) O-antigen. Although there was an incremen
t of these immune functions with the treatment of glucans and O-antige
n compared with controls, they were inhibited at high doses (200 mu g/
ml). The optimum dose of glucan was 50 mu g/ml when it was administere
d alone, but a concentration of 10 mu g/ml was enough to produce the s
timulatory effect.