DESMOPLASTIC FIBROMA OF THE TEMPORAL BONE

Background: Desmoplastic fibroma is a benign, locally aggressive, intr aosseous neoplasm with a propensity for local recurrence. Desmoplastic fibroma most commonly originates within the mandible (70% of cases), and long bones with rare lesions reported in the maxillary, frontal, a nd parietal bones. We report two patients with desmoplastic fibroma ar ising within the temporal bone. Study Design: Case report and literatu re review. Patients: Two patients with desmoplastic fibroma with intra cranial and extra cranial growth patterns are presented. Both were you ng females with aural fullness and decreased hearing. Interventions: D iagnostic and therapeutic. Results: Both tumors were surgically extirp ated and the pa patients have remained disease free for 18-48 months. Neither tumor expressed estrogen or progesterone receptors. Conclusion : Desmoplastic fibroma is a highly invasive local destructive lesion w hich is best treated by nondestructive surgical intervention. Immunohi stochemical analysis may demonstrate hormonal receptors, in which case Tamoxifen may reduce recurrence.