RING TRANSFORMATION OF FUSED PYRIDAZINES .6. CONSTRUCTION OF 3-(2-PYRIDYL)INDOLE SKELETON BY MEANS OF N-N BOND-CLEAVAGE REACTION OF FUSED PYRIDAZINES WITH YNAMINES
K. Iwamoto et al., RING TRANSFORMATION OF FUSED PYRIDAZINES .6. CONSTRUCTION OF 3-(2-PYRIDYL)INDOLE SKELETON BY MEANS OF N-N BOND-CLEAVAGE REACTION OF FUSED PYRIDAZINES WITH YNAMINES, Heterocycles, 45(8), 1997, pp. 1551-1557
We established a new N-N bond cleavage reaction of pyridazino[4,5-b]in
doles with ynamines to form 3-(2-pyridyl)indoles. The latter are easil
y converted to 3-(2-piperidyl)indoles, which are key intermediates for
the synthesis of indole alkaloids.