STUDIES ON ISOCYANIDES AND RELATED-COMPOUNDS - A NOVEL SYNTHETIC ROUTE TO 1,6-DIHYDRO-6-OXOPYRIDINE-2-CARBOXYLIC ACID-DERIVATIVES

Authors
BOSSIO R MARCOS CF MARCACCINI S PEPINO R
Citation
R. Bossio et al., STUDIES ON ISOCYANIDES AND RELATED-COMPOUNDS - A NOVEL SYNTHETIC ROUTE TO 1,6-DIHYDRO-6-OXOPYRIDINE-2-CARBOXYLIC ACID-DERIVATIVES, Heterocycles, 45(8), 1997, pp. 1589-1592
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
45
Issue
8
Year of publication
1997
Pages
1589 - 1592
Database
ISI
SICI code
0385-5414(1997)45:8<1589:SOIAR->2.0.ZU;2-W
Abstract
The Ugi 4-CC between (E)-cinnamaldehyde (2), benzoylformic acid (3), c yclohexyl isocyanide (4) and amines (5) afforded the expected -[N-benz oylformyl-N-arylamino]-4-phenylbut-3-enoic acid N-cyclohexylamides (6) which underwent a base-catalyzed cyclization to give the title compou nds in high yields.