In this article, we look at the literature concerning the relationship
between blood pressure and cognitive function. If untreated, hyperten
sion leads to stroke or cerebral infarction, and may therefore increas
e the risk of dementi a or cognitive impairment. Patients with hyperte
nsion perform less well in some, but not all, cognitive tasks compared
with normotensive individuals, even in the absence of overt stroke. T
he mechanisms underlying hypertension-related cognitive changes are co
mplex and are not yet fully understood. Antihypertensive drug therapy
may prevent cognitive decline, but no longitudinal studies have been p
erformed to verify this in the general population. The relationship be
tween blood pressure and cognition may be more complicated in the very
old than in other age groups.