Relative enophthalmos is often cited as a causative factor in the deve
lopment of involutional entropion. However, the association between en
ophthalmos and involutional entropion is largely anecdotal; no patient
population study has been performed to determine if a causal relation
ship exists. This prospective clinical study compares exophthalmometri
c values in a population of patients with involutional entropion to an
age-and sex-matched control group. Hertel exophthalmometric measureme
nts were obtained on 56 patients with involutional entropion presentin
g over a 2-year period. Exophthalmometric measurements were also obtai
ned in a group of 53 age- and sex-matched control patients presenting
for evaluation and management of unrelated periocular disorders. Fifty
-three patients presented with unilateral entropion and three patients
presented with bilateral lower lid entropion. The mean of exophthalmo
metric measurements was within 16.0 mm in the entropion group and 16.1
5 mm in the control group. Eyes with involutional entropion are no mor
e likely to have enophthalmos than is the uninvolved contralateral eye
or normal eyes of an age-and sex-matched control population. Enophtha
lmos does not appear to play a role in the development of involutional
entropion.