CEREBROVASCULAR COMPLICATIONS AND NEURODEVELOPMENTAL SEQUELAE OF NEONATAL ECMO

The neurologic complications and neurodevelopmental sequelae of neonat al extracorporeal membrane oxygenation (ECMO) are discussed. The labor atory and clinical studies that may be of prognostic significance in t erm of near-term neonates treated with venoarterial ECMO are reviewed. Pathophysiologic mechanisms associated with cardiorespiratory failure and its treatment before and during ECMO that may contribute to an ad verse outcome are reviewed. The potential advantages of venovenous com pared with venoarterial ECMO are considered, and the need for further research is emphasized.