A case of intraorbital ectopic lacrimal gland was evaluated with vario
us radionuclides. CT and MRI with contrast enhancement showed a soft-t
issue mass in the orbit. The lesion was gallium-avid, but F-18-FDG PET
demonstrated very faint uptake. On early and delayed Tl-201-Cl images
, mildly increased uptake and mild retention were observed. Technetium
-99m-(V)-DMSA SPECT showed intense accumulation on both the early and
delayed images. Technetium-99m-pertechnetate SPECT, demonstrating mark
ed uptake in the lesion, was useful for the differential diagnosis bet
ween intraorbital malignancy and this benign lesion. These scintigraph
ic variations played an important role in the tissue characterization
of this uncommon lesion.