Mer. Williamson et al., ONE-STAGE RESTORATIVE PROCTOCOLECTOMY WITHOUT TEMPORARY ILEOSTOMY FORULCERATIVE-COLITIS - A NOTE OF CAUTION, Diseases of the colon & rectum, 40(9), 1997, pp. 1019-1022
PURPOSE: This study was designed to determine the safety of omitting a
temporary defunctioning ileostomy in restorative proctocolectomy for
ulcerative colitis. METHOD: One hundred consecutive patients With ulce
rative colitis were treated electively by restorative proctocolectomy
and pouch-anal anastomosis, without mucosal stripping; 50 had a defunc
tioning ileostomy added, and 50 underwent a one-stage procedure withou
t ileostomy. RESULTS: There was no operative mortality. The incidence
of postoperative complications was similar in the two groups of patien
ts. Life-threatening complications, however, were more common among pa
tients who did not have a defunctioning ileostomy, of whom Il develope
d pelvic sepsis and 7 required reoperation. Among patients with an ile
ostomy, seven developed pelvic sepsis but none required reoperation (P
< 0.02). Emergency reoperations were required in 11 patients without
an ileostomy but in only 1 patient with an ileostomy (P < 0.01). CONCL
USION: One-stage restorative proctocolectomy without a defunctioning i
leostomy is associated with increased risk to life. Its routine use ca
nnot be recommended.