COMPARISON OF THE UTILITY OF CAPILLARY ZONE ELECTROPHORESIS AND HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY IN PEPTIDE-MAPPING AND SEPARATION

Authors
RUDNICK SE HILSER VJ WOROSILA GD
Citation
Se. Rudnick et al., COMPARISON OF THE UTILITY OF CAPILLARY ZONE ELECTROPHORESIS AND HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY IN PEPTIDE-MAPPING AND SEPARATION, Journal of chromatography, 672(1-2), 1994, pp. 219-229
Citations number
11
Categorie Soggetti
Chemistry Analytical
Journal title
Journal of chromatography → ACNP
Volume
672
Issue
1-2
Year of publication
1994
Pages
219 - 229
Database
ISI
SICI code
Abstract
Capillary zone electrophoresis (CZE) and high-performance liquid chrom atography (HPLC) have been used in the analysis of the primary structu re of recombinant human insulin-like growth factor I (rhIGF-I). CZE bo th complements and supplements HPLC separations. CZE has been used to resolve peaks which co-elute on HPLC, as well as to help establish the identity of tryptic fragments in peptide mapping experiments.