A COMPARISON OF ELTANOLONE AND PROPOFOL ANESTHESIA FOR MINOR GYNECOLOGICAL SURGERY

Citation
Ja. Whyte et al., A COMPARISON OF ELTANOLONE AND PROPOFOL ANESTHESIA FOR MINOR GYNECOLOGICAL SURGERY, European journal of anaesthesiology, 14(5), 1997, pp. 499-504
Citations number
14
Categorie Soggetti
Anesthesiology
ISSN journal
02650215
Volume
14
Issue
5
Year of publication
1997
Pages
499 - 504
Database
ISI
SICI code
0265-0215(1997)14:5<499:ACOEAP>2.0.ZU;2-H
Abstract
We have used eltanolone and propofol to induce anaesthesia and by inte rmittent injection to supplement nitrous oxide during maintenance in 6 7 patients undergoing minor gynaecological surgery. This study was a c ontrolled randomized phase III with two parallel groups and a blinded assessment of post-operative recovery. Complications during induction and maintenance were few. Urticaria occurred in two patients given elt anolone and in none of those given propofol. Time to orientation and t ime to eye opening were significantly shorter in the propofol group (P < 0.001). Systolic and diastolic blood pressure decreased in both gro ups but the decrease was significantly greater in the propofol group ( P < 0.005 systolic blood pressure; P < 0.001 diastolic blood pressure) . Heart rate decreased significantly in the propofol group (P < 0.002) . We conclude that eltanolone anaesthesia is associated with a greater haemodynamic stability than propofol anaesthesia but that early recov ery occurs more slowly.