TEMPORAL RELATIONSHIPS BETWEEN PULSATILE CORTISOL SECRETION AND ELECTROENCEPHALOGRAPHIC ACTIVITY DURING SLEEP IN MAN

Citation
C. Gronfier et al., TEMPORAL RELATIONSHIPS BETWEEN PULSATILE CORTISOL SECRETION AND ELECTROENCEPHALOGRAPHIC ACTIVITY DURING SLEEP IN MAN, Electroencephalography and clinical neurophysiology, 103(3), 1997, pp. 405-408
Citations number
15
Categorie Soggetti
Clinical Neurology
ISSN journal
00134694
Volume
103
Issue
3
Year of publication
1997
Pages
405 - 408
Database
ISI
SICI code
0013-4694(1997)103:3<405:TRBPCS>2.0.ZU;2-Y
Abstract
A temporal link between slow wave sleep and low or decreasing cortisol release has been previously demonstrated. This relationship was re-ev aluated in 15 healthy male subjects using spectral analysis of their s leep electroencephalogram (EEG). EEG activity in the delta, theta, alp ha and beta bands was cross-correlated with cortisol secretory rates a t 10-min intervals. For the period of pulsatile cortisol secretion, an inverse relationship was found with the delta band with an average cr oss-correlation coefficient of -0.505 (P < 0.0001). Variations in cort isol secretory rates coincided with or anticipated opposite variations in delta wave activity by 10 or 20 min. A significant positive correl ation was found with theta activity, but alpha and beta bands did not elicit any systematic association with cortisol profiles. These result s demonstrate a temporal association between cortisol secretory pulses and delta wave activity in man, suggesting the existence of a central control common to both variables. (C) 1997 Elsevier Science Ireland L td.