A NEURAL-NETWORK FOR THE SIMULATION OF BIOLOGICAL-SYSTEMS

It has been shown that a self-organizing neural network can be assembl ed with a single instar neuron to provide a method for the efficient a nalysis of biological data. The method properly models the affinities of the selected compounds to the CBG, TBG (corticosteroid and testoste rone binding globulins) and sweet taste receptor-sites. The influence of some parameters on the efficiency of the network has been analysed and alternative statistical analysis of the atomic coordinates and cha rges has been performed. (C) 1997 Elsevier Science B.V.