SYNTHESIS OF SOME ACRIDONE ALKALOIDS AND RELATED-COMPOUNDS

Authors
CHEN JJ DEADY LW MACKAY MF
Citation
Jj. Chen et al., SYNTHESIS OF SOME ACRIDONE ALKALOIDS AND RELATED-COMPOUNDS, Tetrahedron, 53(37), 1997, pp. 12717-12728
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
37
Year of publication
1997
Pages
12717 - 12728
Database
ISI
SICI code
0040-4020(1997)53:37<12717:SOSAAA>2.0.ZU;2-8
Abstract
An efficient Pd/C aromatization of 1,2,3,4,9,10-hexahydroacridine-1,9- diones to 1-hydroxyacridones is reported. The previously reported four -step synthesis of the diones has been extended to give a number of me thoxy substituted derivatives and the aromatization reaction, along wi th hydrobromic acid demethylation, provides a useful route to various methoxy and hydroxy substituted acridones. (C) 1997 Published by Elsev ier Science Ltd.