EFFICIENT GENERATION AND INTRAMOLECULAR CYCLIZATION REACTIONS OF ACYLIMINES

Authors
DENINNO MP ELLER C
Citation
Mp. Deninno et C. Eller, EFFICIENT GENERATION AND INTRAMOLECULAR CYCLIZATION REACTIONS OF ACYLIMINES, Tetrahedron letters, 38(37), 1997, pp. 6545-6548
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
37
Year of publication
1997
Pages
6545 - 6548
Database
ISI
SICI code
0040-4039(1997)38:37<6545:EGAICR>2.0.ZU;2-4
Abstract
Acyl carbamates can be selectively reduced with diisobutyl aluminum hy dride to provide high yields of N-acyl hemiaminals 1. With appropriate substitution, these intermediates undergo Lewis acid catalyzed intram olecular exo cyclization reactions to afford l-amino 1,2,3,4-tetrahydr onaphthalene derivatives. (C) 1997 Elsevier Science Ltd.