TOSYLMETHYLAMINES AS NONSTABILIZED ALPHA-AMINOCARBANION SYNTHON EQUIVALENTS - ADVANTAGES AND LIMITATIONS

Authors
KATRITZKY AR FENG DM QI M
Citation
Ar. Katritzky et al., TOSYLMETHYLAMINES AS NONSTABILIZED ALPHA-AMINOCARBANION SYNTHON EQUIVALENTS - ADVANTAGES AND LIMITATIONS, Journal of organic chemistry, 62(18), 1997, pp. 6222-6225
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
62
Issue
18
Year of publication
1997
Pages
6222 - 6225
Database
ISI
SICI code
0022-3263(1997)62:18<6222:TANASE>2.0.ZU;2-6
Abstract
Tosylmethylamines (1) are advantageous synthon equivalents for ''nonst abilized'' alpha-aminocarbanions of aromatic amines, Clean reactions a nd high yields are observed provided one-step procedures are utilized: the intermediate ''nonstabilized'' alpha-aminocarbanions are of low s tability, Reactions formally involving dianions from bis(tosylmethyl)- substituted amines have also been achieved.