A survey on the management of hepatitis C virus (HCV) infection was co
nducted by the American Digestive Health Foundation among United State
s physicians who are most familiar with the disease. The two-page surv
ey was completed by 57% of a random sample of 2,500 members of the Ame
rican Gastroenterological Association and the American Association for
the Study of Liver Diseases. Analysis was limited to the 1,249 respon
ses from physicians who spent at least 1 day per week in patient care.
These physicians frequently managed patients with HCV, and nearly thr
ee quarters treated patients with interferon. To prevent transmission,
the large majority of physicians recommended measures to avoid blood
exposures, were uncertain or disagreed about the importance of sexual
contact, and did not caution patients about casual contact. More than
70% of physicians told their patients to stop or minimize alcohol cons
umption. In the management of a patient with antibody to HCV but norma
l serum aminotransferase activities, 87% of physicians would have orde
red a supplemental lest, and if HCV mere confirmed, 46% would have obt
ained a liver biopsy, but only 15% would have treated the patient with
interferon. For a patient with chronic HCV infection and elevated ser
um aminotransferase activities, more than 90% of physicians mould have
obtained a liver biopsy and approximately 60% would have treated with
interferon. Physicians who are most familiar with the management of p
atients with HCV generally agreed with the recommendations of the Cons
ensus Development Conference Panel regarding prevention of transmissio
n, minimizing alcohol consumption, and managing patients with typical
presentations, Controversies remain regarding some issues of general m
anagement, the value of molecular resting, and the need to treat certa
in patients with interferon.