Objective - To determine long-term outcome of dogs with neoplastic and
nonneoplastic pericardial disease that undergo pericardiectomy. Desig
n - Retrospective study. Animals - 22 dogs. Procedure - Dogs that unde
rwent pericardiectomy and in which the diagnosis had been confirmed hi
stologically were included. Data collected from each record included s
ignalment, history, clinical signs, results of diagnostic evaluations,
operative management, postoperative complications, histologic diagnos
is, and outcome. Dogs were grouped on the basis of underlying cause of
pericardial disease (neoplastic vs nonneoplastic), and survival times
were determined by means of Kaplan-Meier analyses. Results - 9 dogs h
ad neoplastic pericardial disease (chemodectoma. 4; hemangiosarcoma. 2
; malignant mesothelioma. 2; lymphoblastic lymphoma, 1). Thirteen dogs
had nonneoplastic pericardial disease (benign idiopathic pericarditis
, 10; lymphocytic-plasmacytic pericarditis, 2; osseous metaplasia of u
nknown cause, 1). Thoracic radiography and echocardiography were the m
ost specific methods for diagnosis of pericardial effusion. Pleural ef
fusion was the most common postoperative complication (8/22 dogs). Pre
valence of postoperative complications was not associated with underly
ing cause of pericardial disease, surgical approach, or surgical proce
dure (subtotal vs total pericardiectomy). Median survival time of dogs
with neoplastic disease (52 days) was significantly shorter than medi
an survival time of dogs with nonneoplastic disease (792 days). Dogs t
hat developed pleural effusion > 30 days after pericardiectomy had a p
oor prognosis for survival. Clinical Implications - Radiography and ec
hocardiography are useful for diagnosis of pericardial effusion in dog
s. Dogs with neoplastic pericardial disease have a significantly short
er survival time than do dogs with nonneoplastic pericardial disease.