With the proposed introduction of a flexible sigmoidoscopic screening
programme for colorectal cancer, patient compliance is of paramount im
portance, Therefore, the bowel preparation providing optimum cleansing
of the bowel with the least associated discomfort and inconvenience f
or the patient must be found. Patients were randomized to receive eith
er Picolax the evening before the examination or self-administered Fle
et enemas prior to the investigation, The endoscopist and nurse practi
tioner who collected data on a standard questionnaire were blinded to
the preparation used. Bowel preparation was graded by the endoscopist
as: excellent, good, adequate or poor, One hundred and two consecutive
patients were randomized: 55 to the Fleet enema group and 46 to the P
icolax group, Self-administered Fleet enemas provided a significantly
superior bowel preparation with 52 (93%) being judged adequate or bett
er, as opposed to 34 (74%) in the Picolax group, In addition, meet ene
mas were associated with significantly fewer adverse associated sympto
ms: 11 (20%) vs 24 (52%). Patients reported to be willing to receive F
leet enemas again in 53 (95%) vs 37 (80%) for the Picolax group. The s
elf-administered Fleet enema is superior to Picolax in terms of bowel
preparation for flexible sigmoidoscopy and the incidence of associated
adverse symptoms.