Gj. Vannooten et al., HUFNAGEL PROCEDURE RECONVERTED BY ENDOVASCULAR LEAFLET DISLOCATION AND EXTIRPATION, Journal of heart valve disease, 6(5), 1997, pp. 546-549
Before the development of standard aortic valve replacement, Hufnagel
treated aortic insufficiency by implanting a ball-valve prosthesis in
the descending thoracic aorta. In a patient who, after four major thor
acic procedures, ultimately received two mechanical bileaflet valves i
n series (one in the ascending and one in the descending aorta), the d
ownstream prosthesis became progressively immobilized, with total bloc
kage of the leaflets in the open position due to insufficient transval
vular negative pressure gradient, After evaluation of this particular
situation in an experimental model, we predicted blockage of the downs
tream prosthesis, once the ascending valve had regained normal functio
n, and easily cleared the blockage of the distal valve by removing the
two leaflets using balloon inflation. Normal circulation was clinical
ly restored in three separate steps. (a) Normal function was re-establ
ished surgically in the ascending aorta position. (b) A second thoraco
tomy was avoided by endovascular dislocation of both blocked descendin
g thoracic leaflets through endovascular balloon inflation. (c) Both l
eaflets embolized to the level of the left common iliac artery, where
the nearly intact leaflets were removed. surgically, finally creating
a near-normal circulatory situation.