Pericarditis is a rare side effect of chemotherapy. We report here the
case of a patient treated with high-dose cytosine arabinoside (HD ara
-c) who developed severe pericarditis. Interruption of HD ara-c and in
itiation of corticosteroid treatment were effective in resolving the p
ericardial effusion. This case illustrates this rare but potentially l
ife-threatening cardiac complication of HD ara-c therapy as well as th
e beneficial effect of corticosteroid treatment.