THERE SHOULD NEVER BE ANOTHER ANTIARRHYTHMICS VERSUS IMPLANTABLE DEFIBRILLATOR (AVID) TRIAL

Authors
SINGER I NISAM S
Citation
I. Singer et S. Nisam, THERE SHOULD NEVER BE ANOTHER ANTIARRHYTHMICS VERSUS IMPLANTABLE DEFIBRILLATOR (AVID) TRIAL, The American journal of cardiology, 80(6), 1997, pp. 766
Citations number
41
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
The American journal of cardiology → ACNP
ISSN journal
00029149
Volume
80
Issue
6
Year of publication
1997
Database
ISI
SICI code
0002-9149(1997)80:6<766:TSNBAA>2.0.ZU;2-F
Abstract
The Antiarrhythmics Versus Implantable Defibrillator (AVID) trial was halted recently, following a demonstration of 38% improved survival at 1 year in patients randomized to defibrillators. Although the trial r eaffirms the superiority of implantable cardiac defibrillators over an tiarrhythmic drugs for therapy of aborted sudden arrhythmic death, the authors provide an opinion that the trial was unnecessary and that th e trial was flawed, raising serious scientific and ethical questions a bout the trial's conduct.