SHIGELLA SEROGROUPS IDENTIFIED FROM ADULT DIARRHEAL OUT-PATIENTS IN ADDIS-ABABA, ETHIOPIA - ANTIBIOTIC-RESISTANCE AND PLASMID PROFILE ANALYSIS

Authors
MACHE A MENGISTU Y COWLEY S
Citation
A. Mache et al., SHIGELLA SEROGROUPS IDENTIFIED FROM ADULT DIARRHEAL OUT-PATIENTS IN ADDIS-ABABA, ETHIOPIA - ANTIBIOTIC-RESISTANCE AND PLASMID PROFILE ANALYSIS, East African medical journal, 74(3), 1997, pp. 179-182
Citations number
21
Categorie Soggetti
Medicine, General & Internal
Journal title
East African medical journal → ACNP
ISSN journal
0012835X
Volume
74
Issue
3
Year of publication
1997
Pages
179 - 182
Database
ISI
SICI code
0012-835X(1997)74:3<179:SSIFAD>2.0.ZU;2-C
Abstract
Fifty shigella strains were isolated from 700 diarrhoeal samples colle cted from adult diarrhoeal out-patients in Addis Ababa. Among the isol ates, serogroup A comprised 28%, B44%, C18% and D10%. Among all shigel la serogroups, highest resistance was encountered to tetracycline(74%) , ampicillin(70%), cephalothin (64%), trimethoprim-sulfamethoxazole(52 %) and chloramphenicol(50%) while least resistance was observed to gen tamicin(0%), polymyxin B(10%) and nalidixic acid(14%). Gentamicin, pol ymyxin B and nalidixic acid were found to be the drugs of choice for c ases of shigellosis. All drug resistant isolates analysed for plasmids contained multiple plasmids ranging from 1.8 to greater than 21 Kilob ases.