Background. The surgical treatment of cancer of the cardia is controve
rsial and results are often disappointing. Concern exists not only wit
h regards to the surgical approach but also to the extent of the resec
tion. The authors analyze their experience over a 20-year period adopt
ing almost exclusively a ''limited'' esophagogastrectomy with a wide r
egional lymphadenectomy through a left thoracotomy. The aim of the stu
dy is to determine if this approach actually plays a role in the treat
ment of this tumor. Methods. 148 patients were evaluated for cardial c
ancer. Of these 22 (14.8%) were not resectable and 6 (4%) received oth
er types of resections for technical reasons. 120 patients are the bas
is of the present analysis. More than 75% of patients were in stage II
I or IV. Follow-up was completed in 92.5% of cases; all surviving pati
ents had at least 5 years of follow-up. Results. Four (3.3%) patients
died in the postoperative period. In 6 cases (5%) an anastomotic leaka
ge occurred and this caused the death of 2 patients. Nine (7.5 %) pati
ents had severe pulmonary complications. Dysphagia was relieved in all
non complicated patients. 13 (10.8%) patients had anastomotic recurre
nce, Overall survival I ate after 5 years was 25.62+/-6.1%. A signific
ant difference in survival was noted in patients at stages II and III
after 5 years (61.3% vs 18.6, p<0.02). Conclusions. This operation has
proved to be a good option providing satisfying long-term results and
a lower incidence of complications if compared with more extended pro
cedures. It can be performed in the majority of patients with carcinom
a of the cardia with a low mortality and morbidity and with excellent
palliation of dysphagia, In our opinion it remains an optimum treatmen
t for cardial cancer.